Research at the Cavite State University began with the conversion of Indang Rural High School into Don Severino Agricultural College in 1964. Since then, the Research Center has evolved to function as one of the trilogy roles of the University. To date, the University is the seat of the national research, development and extension for coffee and urban agriculture - a status bestowed by the Department of Agriculture Bureau of Agricultural Research.
The Research Center (RC) exerted serious efforts towards streamlining the Research, Development and Extension Program by establishing a strong and effective research program aimed to generate innovative and viable technologies useful to farmers and other clienteles. This is done with the goal of improving their standard of living. The University's research program focused on two major programs: Coffee Research, Development and Extension and Urban Agriculture Research, Development and Extension. These two major thrusts provide the framework for an organized research and extension. However, to accommodate the ever increasing need for RD&E activities brought about by the development of the university into a comprehensive one, there thrusts have become more elaborated trough the "Faculty and Students Research Capability Enhancement Program" that has been approved by the University Board of Regents in 2004. Moreover, a MOU with Happy Earth Organization, a non-governmental organization, for RD&E activities on ARENGA PINNATA (kaong) was signed on 2004.
The University has also maintained ties and establishing collaborative projects with international and local agencies with emphasis on plantation crops, high value fruits and vegetables, poultry and livestock, and ornamentals among others.